Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol CDKN2C
Synonyms INK4C | p18 | p18-INK4C
Gene Description CDKN2C, cyclin-dependent kinase 4 inhibitor 2C, interacts with CDK6 and CDK4, and inhibits cell growth and proliferation with a correlated dependence on endogenous RB1 (PMID: 19147556). CDKN2C loss has been observed in sporadic medullary thyroid carcinoma patients with decreased survival (PMID: 27610696, PMID: 31648931) and decreased expression has been observed in acute promyelocytic leukemia (PMID: 27888400).


Additional content available in CKB BOOST