Gene Detail

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Gene Symbol CDX2
Synonyms CDX-3 | CDX2/AS | CDX3
Gene Description CDX2, caudal type homeobox 2, is a member of the caudal-related homeobox transcription factor family and regulates processes including adhesion, cell proliferation, differentiation, migration, and tumorigenesis (PMID: 21126581). An ETV6-CDX2 fusion has been identified in acute myeloid leukemia (PMID: 9920852) and expression of Cdx2 has been associated with intestinal-type intraductal papillary mucinous neoplasm (PMID: 32291497) and altered expression has been reported in colorectal cancer (PMID: 32117703).


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