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Gene Symbol CARM1
Synonyms PRMT4
Gene Description CARM1, coactivator-associated arginine methyltransferase 1, is a type 1 arginine methyltransferase that acts in the regulation of transcription, pre-mRNA splicing, cell cycle progression and the DNA damage response. There are conflicting reports of Carm1 activity in normal and tumor cells, possibly due to different transcripts (PMID: 24921003), but overexpression has been correlated with invasive breast cancer and lung cancer (PMID: 23915145, PMID: 24211191).


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