Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | CARM1 | ||||||||||
| Synonyms | PRMT4 | ||||||||||
| Gene Description | CARM1, coactivator associated arginine methyltransferase 1, is a type 1 arginine methyltransferase that acts in the regulation of transcription, pre-mRNA splicing, cell cycle progression and the DNA damage response (PMID: 32011657). There are conflicting reports of Carm1 activity in normal and tumor cells, possibly due to different transcripts (PMID: 24921003), but overexpression has been correlated with invasive breast cancer and lung cancer (PMID: 23915145, PMID: 24211191). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
