Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | ATG7 | ||||||||||
| Synonyms | APG7-LIKE | APG7L | GSA7 | SCAR31 | ||||||||||
| Gene Description | ATG7, ubiquitin-like modifier-activating enzyme ATG7, is an E1-like activating enzyme involved in autophagy, a process involved in lysosome degradation (PMID: 29311554). An ATG7-BRAF fusion has been identified in cutaneous melanoma (PMID: 26091043) and ATG7-RAF1 fusions have been associated with anaplastic pleomorphic xanthoastrocytoma (PMID: 27624885) and pediatric high-grade gliomas (PMID: 28912153). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
