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Gene Symbol ATG7
Synonyms APG7-LIKE | APG7L | GSA7
Gene Description ATG7, ubiquitin-like modifier-activating enzyme ATG7, is an E1-like activating enzyme involved in autophagy, a process involved in lysosome degradation (PMID: 29311554). An ATG7-BRAF fusion has been identified in cutaneous melanoma (PMID: 26091043) and ATG7-RAF1 fusions have been associated with anaplastic pleomorphic xanthoastrocytoma (PMID: 27624885) and pediatric high-grade gliomas (PMID: 28912153).


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