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Gene Symbol GNA13
Synonyms G13 | HG1N
Gene Description GNA13, G protein subunit alpha 13, encodes a member of the G12 family of G protein alpha subunits, which activate Rho guanine-exchange factors and play a role in cell migration and invasion (PMID: 19422395, PMID: 19226283). GNA13 mutations have been identified in Burkitt’s lymphoma and defuse large B-cell lymphoma (PMID: 26616858, PMID: 23699601), and altered expression levels have been identified in multiple malignancies including hepatocellular carcinoma (PMID: 27883022), and gastric cancer (PMID: 26735177).
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