Gene Detail

Gene Symbol POLQ
Synonyms PRO0327
Gene Description POLQ, DNA polymerase theta, is a promiscuous DNA polymerase that regulates microhomology-mediated end-joining in response to double-stranded DNA breaks (PMID: 25642963). POLQ expression is elevated in epithelial ovarian cancers and is associated with homologous recombination activity (PMID: 25642963).
Entrez Id 10721
Chromosome 3
Map Location 3q13.33
Canonical Transcript NM_199420

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