Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | PNRC1 | ||||||||||
| Synonyms | B4-2 | PNAS-145 | PROL2 | PRR2 | ||||||||||
| Gene Description | PNRC1, proline rich nuclear receptor coactivator 1, acts as a co-activator for nuclear receptors such as SF1, PR, ERR-alpha1, and TR (PMID: 10894149), and is a putative tumor suppressor, playing a role in regulation of ribosomal RNA processing and thereby regulating cell proliferation (PMID: 30373810, PMID: 30455174). PNRC1 copy number loss and decreased gene expression has been identified in several tumor types (PMID: 30373810). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
