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Gene Symbol CPSF6
Synonyms CFIM | CFIM68 | CFIM72 | HPBRII-4 | HPBRII-7
Gene Description CPSF6, cleavage and polyadenylation specificity factor subunit 6, is a component of the cleavage factor I (CFIm), which is a multisubunit complex that plays a role in the processing of RNA (PMID: 28673861). A RARG-CPSF6 fusion has been observed in AML (PMID: 29891591), a CPSF6-FGFR1 fusion in myeloproliferative syndrome (PMID: 18205209), and Cpsf6 may play a role in the aggressiveness of breast cancer (PMID: 28673861).
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