Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol BTN3A1
Synonyms BT3.1 | BTF5 | BTN3.1 | CD277
Gene Description BTN3A1, butyrophilin subfamily 3 member A1, encodes a member of the butyrophilin family, which plays a role in the regulation of T cells, specifically gammadelta T cells, thereby, facilitating immune response and control of immune homeostasis (PMID: 25637025, PMID: 29670629). BTN3A1 overexpression has been observed in ovarian cancer (PMID: 32820120), pancreatic adenocarcinoma (PMID: 30906655), and expression of BTN3A1 has been identified in colorectal cancer (PMID: 28405500).


Additional content available in CKB BOOST