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Gene Symbol POLI
Synonyms eta2 | RAD30B | RAD3OB
Gene Description POLI, DNA polymerase iota, is an error-prone Y family DNA polymerase, which is involved in translesion DNA synthesis (PMID: 23922701, PMID: 23955086, PMID: 28865289). Overexpression of Poli may promote cell migration and invasion in breast cancer (PMID: 30829610), lung cancer (PMID: 30060029), and esophageal squamous cell carcinoma (PMID: 28905458).
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