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Gene Symbol BORCS5
Synonyms LOH12CR1 | LOH1CR12
Gene Description BORCS5, BLOC-1 related complex subunit 5, is a member of the BORC complex that functions to regulate lysosomal positioning (PMID: 25898167). A BORCS5-ETV6 fusion has been identified in gastric cancer (PMID: 31222839) and an LMO3-BORCS5 fusion has been identified in Ewing sarcoma (PMID: 31488873), and decreased expression of BORCS5 has been demonstrated in colorectal carcinoma (PMID: 29879888).
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