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Gene Symbol CREB1
Synonyms CREB | CREB-1
Gene Description CREB1, cAMP responsive element binding protein 1, encodes for a transcription factor, which upon phosphorylation, induces cellular gene transcription in part via the CREB-binding protein/p300 paralog (PMID: 15753290). CREB1 fusions with EWSR1 have been observed in sarcomas (PMID: 25134518) and Creb1 overexpression has been observed to induce cell proliferation in gastric cancer cells (PMID: 28498439).


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