Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | CTNNA2 | ||||||||||
| Synonyms | CAP-R | CAPR | CDCBM9 | CT114 | CTNR | ||||||||||
| Gene Description | CTNNA2, catenin alpha 2, encodes a protein that forms a link between cadherin receptors and actin filaments and regulates cell adhesion, differentiation, and cytoskeletal organization, and controls neuron growth and migration (PMID: 25673211, PMID: 30013181). CTNNA2 mutations have been observed in gastric (PMID: 24816253), pancreatic (PMID: 28679692), and laryngeal (PMID: 24100690) cancers, and decreased CTNNA2 expression has been identified in neuroblastoma (PMID: 31489113) and esophageal cancer (PMID: 30526004). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
