Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | CTNND1 | ||||||||||
| Synonyms | BCDS2 | CAS | CTNND | p120 | p120(CAS) | p120(CTN) | P120CAS | P120CTN | ||||||||||
| Gene Description | CTNND1, catenin delta 1, encodes for p120-catenin, which plays a role in cell adhesion via association with E-cadherin, resulting in the regulation and stability of cadherins found at the cellular membrane (PMID: 23071139). CTNND1 amplification has been identified in lung cancer (PMID: 20715154), CTNND1 loss has been associated with breast cancer (PMID: 23733751), CTNND1 overexpression has been reported in hepatocellular carcinoma (PMID: 27193094), and a CTNND1 missense mutation has been observed in metastatic urothelial carcinoma (PMID: 31192134). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
