Gene Detail

Gene Symbol KLB
Synonyms BKL
Gene Description KLB, klotho beta, is a transmembrane protein that interacts with Fgfrs to promote high affinity Fgf binding, therefore regulates cell metabolism and growth (PMID: 18772362, PMID: 20657013). Overexpression of KLB have been identified in bladder and liver cancers (PMID: 27573985, PMID: 22439738).
Entrez Id 152831
Chromosome 4
Map Location 4p14
Canonical Transcript NM_175737

Additional content available in CKB BOOST