Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||CPT7 | CYP17 | P450C17 | S17AH|
|Gene Description||CYP17A1, cytochrome P450 family 17 subfamily A member 1, is an enzyme that catalyzes the addition of a hydroxyl group to pregnenolone and progesterone, and cleaves the hydroxylated intermediates to synthesize androgens and corticoids (PMID: 29372682, PMID: 21051590, PMID: 27748439). Overexpression of Cyp17a1 is associated with poor prognosis in glioma (PMID: 28530704).|