Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||DHOdehase | POADS | URA1|
|Gene Description||DHODH, dihydroorotate dehydrogenase (quinone), is a mitochondrial enzyme that reversibly catalyzes the oxidation of dihydroorotate to orotate, and plays an important role in de novo pyrimidine biosynthesis (PMID: 28666740, PMID: 6105839). Activation of DHODH may play a role in tumorigenesis (PMID: 29925003, PMID: 30449682, PMID: 32151633).|