Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | DNMT3B | ||||||||||
| Synonyms | FSHD4 | ICF | ICF1 | M.HsaIIIB | ||||||||||
| Gene Description | DNMT3B, DNA methyltransferase 3 beta, is a de novo DNA methyltransferase involved in establishing methylation state during development (PMID: 24822169). Overexpression of Dnmt3b has been reported in several tumor types and is associated with hypermethylation in tumor pathogenesis (PMID: 24822169), and both amplification and overexpression have been observed in colorectal cancer (PMID: 32058953). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
