Gene Detail

Gene Symbol APLNR
Synonyms AGTRL1 | APJ | APJR | HG11
Gene Description APLNR, apelin receptor, is a G-protein coupled receptor that plays a role in a variety of physiological processes related to maintaining homeostasis including angiogenesis, cardiovascular function, fluid homeostasis, and metabolism (PMID: 23943882). Loss of function APLNR mutations, which are associated with reduced T-cell function, have been identified in lung cancer and melanoma (PMID: 28783722).
Entrez Id 187
Chromosome 11
Map Location 11q12.1
Canonical Transcript NM_005161

Additional content available in CKB BOOST