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|Synonyms||eIF-1A | eIF-4C | EIF1A | EIF1AP1 | EIF4C|
|Gene Description||EIF1AX, eukaryotic translation initiation factor 1A X-linked, encodes a protein that stimulates 43S ternary complex formation, which initiates protein translation (PMID: 24499181), and is essential for cell proliferation (PMID: 30420357). EIF1AX mutations have been identified in uveal melanoma (PMID: 23793026, PMID: 27123562), low-grade serous ovarian carcinoma (PMID: 28646021), and thyroid neoplasms (PMID: 26911375).|