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Gene Symbol APOBEC3A
Synonyms A3A | ARP3 | bK150C2.1 | PHRBN
Gene Description APOBEC3A, apolipoprotein B mRNA editing enzyme catalytic subunit 3A, deaminates single stranded DNA acting as a host defense against retroviruses and foreign DNA (PMID: 22001110, PMID: 23977391). APOBEC3A is able to hypermutate somatic DNA, which may impact onset and progression of cancer (PMID: 23977391), and overexpression has been observed in breast cancer (PMID: 32176735, PMID: 31841499).


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