Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol EPHB2
Synonyms BDPLT22 | CAPB | DRT | EK5 | EPHT3 | ERK | Hek5 | PCBC | Tyro5
Gene Description EPHB2, EPH receptor B2, is a receptor tyrosine kinase that binds to ephrin-B family of ligands and mediates downstream signaling, which is involved in regulation of cell proliferation and tumorigenesis (PMID: 19962662). Overexpression of Ephb2 has been associated with poor prognosis in prostate cancer (PMID: 31805710) and has been observed in gastric cancer (PMID: 32226496) and colorectal cancer (PMID: 30016858).


Additional content available in CKB BOOST