Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | EPS15 | ||||||||||
| Synonyms | AF-1P | AF1P | MLLT5 | ||||||||||
| Gene Description | EPS15, epidermal growth factor receptor pathway substrate 15, is a putative dynamin-homolog that functions in recycling of endosomes from the plasma membrane (PMID: 32041776) and includes recycling of the EGFR receptor (PMID: 30214560). An EPS15-BRAF fusion has been identified in lung adenocarcinoma (PMID: 26314551), while Eps15 expression may play a role in angiogenesis in non-small cell lung cancer (PMID: 31023336) and overexpression in osteosarcoma has been associated with decreased survival (PMID: 30975166). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
