Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol ERCC1
Synonyms COFS4 | RAD10 | UV20
Gene Description ERCC1, ERCC excision repair 1, endonuclease non-catalytic subunit, forms part of an endonuclease complex that functions in DNA repair (PMID: 26074087). ERCC1 expression level has been correlated with response to platinum-based therapies in various tumor types, including ovarian, non-small cell lung, and head and neck cancers (PMID: 26804248, PMID: 26179868, PMID: 26870207).


Additional content available in CKB BOOST