Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||ARMD5 | CKN2 | COFS | COFS1 | CSB | CSB-PGBD3 | POF11 | RAD26 | UVSS1|
|Gene Description||ERCC6, ERCC excision repair 6, chromatin remodeling factor, is a DNA-dependent ATPase that participates in DNA repair and transcription (PMID: 23562425). Mutations in ERCC6 have been associated with increased risks of developing gastric (PMID: 24289633) and lung cancers (PMID: 18789574, PMID: 17854076), while increased expression has been associated with poor prognosis in gastric cancer (PMID: 30417012), and ERCC6 may be a driver gene in neuroblastoma (PMID: 30012197).|