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|Synonyms||HIHGHH | PKBB | PKBBETA | PRKBB | RAC-BETA|
|Gene Description||AKT2, RAC-beta serine/threonine-protein kinase, regulates a number of cell functions, including proliferation, survival, growth, angiogenesis, and metabolism through PI3K signaling (PMID: 28557977). Amplification and overexpression of Akt2 has been identified in a variety of solid tumor types (PMID: 7657393, PMID: 29199386, PMID: 29374601) and is downregulated by several micro-RNAs to inhibit cell migration and invasion (PMID: 28586057, PMID: 28548936, PMID: 28534950).|