Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||FA3 | FAC | FACC|
|Gene Description||FANCC, FA complementation group C, is a member of the Fanconi anemia core complex, which plays a role in DNA repair (PMID: 22675617, PMID: 27145721). Germline FANCC mutations are associated with Fanconi anemia, which involves predisposition to various cancers (PMID: 32235514), including pancreatic cancer (PMID: 15695377, PMID: 32113160) and colorectal cancer (PMID: 27165003), although some FANCC truncating mutations do not increase breast cancer risk (PMID: 31467304).|