Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol JMJD1C
Synonyms KDM3C | TRIP-8 | TRIP8
Gene Description JMJD1C, jumonji domain containing 1C, encodes a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation (PMID: 17549425). JMJD1C expression and mutations are associated with various tumor types (PMID: 17549425; PMID: 24501218; PMID: 24896186) and specifically, overexpression has been observed in MLL-rearranged leukemia (PMID: 31076406) and esophageal cancer (PMID: 28123852).
Additional content available in CKB BOOST