Gene Detail

Gene Symbol FEN1
Synonyms FEN-1 | MF1 | RAD2
Gene Description FEN1, flap endonuclease 1, belongs to the Rad2 structure-specific nuclease family (PMID: 20929870) and plays a role in DNA replication, DNA repair, telomere maintenance, and genomic stability (PMID: 28187440). Overexpression of Fen1 may be a marker of genomic instability and poor prognosis in pancreatic adenocarcinoma (PMID: 29735403) and NSCLC (PMID: 29037854).
Entrez Id 2237
Chromosome 11
Map Location 11q12.2
Canonical Transcript NM_004111


Additional content available in CKB BOOST