Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||FEN-1 | MF1 | RAD2|
|Gene Description||FEN1, flap endonuclease 1, belongs to the Rad2 structure-specific nuclease family (PMID: 20929870) and plays a role in DNA replication, DNA repair, telomere maintenance, and genomic stability (PMID: 28187440). Overexpression of Fen1 may be a marker of genomic instability and poor prognosis in pancreatic adenocarcinoma (PMID: 29735403) and NSCLC (PMID: 29037854).|