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Gene Symbol PDZRN3
Synonyms LNX3 | SEMACAP3 | SEMCAP3
Gene Description PDZRN3, PDZ domain containing ring finger 3, is an E3 ubiquitin ligase that is involved in cell differentiation (PMID: 17118964, PMID: 20668165, PMID: 23576576), development (PMID: 17576800, PMID: 25198863, PMID: 29779941), and suppression of apoptosis (PMID: 31980707). PDZRN3 fusions have been identified in spindle cell tumors (PMID: 30742323), pancreatic acinar cell carcinomas (PMID: 32358589), and perivascular epithelioid cell neoplasms (PMID: 25651471).
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