Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol KDM4B
Synonyms JMJD2B | TDRD14B
Gene Description KDM4B, lysine (K)-specific demethylase 4B, is a Jumonji domain histone demethylase, regulating gene transcription through chromatin remodeling to affect cell growth and differentiation (PMID: 24349617). KDM4B expression may play a role in prostate cancer, ER-positive breast cancer (PMID: 24349617) and amplifies p53-dependent growth of colon cancer cells (PMID: 28073943).


Additional content available in CKB BOOST