Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol KDM4C
Synonyms GASC1 | JHDM3C | JMJD2C | TDRD14C
Gene Description KDM4C, lysine demethylase 4C, is a Jumonji domain histone demethylase, regulating gene transcription through chromatin remodeling to affect cell growth and differentiation (PMID: 24349617) and chromosome stability (PMID: 30083054). KDM4C overexpression had been reported in numerous cancers (PMID: 24349617), including prostate (PMID: 31766290) and breast (PMID: 31784197, PMID: 30083054).
Additional content available in CKB BOOST