Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol NFASC
Synonyms NEDCPMD | NF | NRCAML
Gene Description NFASC, neurofascin, is a a member of the immunoglobulin superfamily of adhesion molecules (PMID: 28418179) and plays a role in neurite out-growth, synaptogenesis, and axonal guidance (PMID: 22306302). A NFASC-NTRK1 fusion has been identified in glioblastoma multiforme (PMID: 24647444) and amplification and overexpression of Nfasc has been observed in lung cancer (PMID: 28418179).


Additional content available in CKB BOOST