Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||BDPLT21 | EWSR2 | FLI-1 | SIC-1|
|Gene Description||FLI1, Fli-1 proto-oncogene, ETS transcription factor, is a member of the Ets transcription family and is involved in embryogenesis and hematopoiesis (PMID: 11175359), and regulates a number of genes involved in the the cell cycle (PMID: 31846072). The fusion protein EWSR1-FLI1 can result in malignant transformation and is commonly found in Ewing sarcoma (PMID: 19417137, PMID: 31649319) and expression in breast cancer was observed to be associated with the immune infiltrate level in breast cancer (PMID: 32249526).|