Gene Detail

Gene Symbol HEY1
Synonyms BHLHb31 | CHF2 | HERP2 | HESR1 | hHRT1 | HRT-1 | NERP2 | OAF1
Gene Description HEY1, hes related family bHLH transcription factor with YRPW motif 1, functions as a downstream effector of the NOTCH signaling pathway, and plays a role in cell proliferation and differentiation (PMID: 28468863, PMID: 27129302). Increased HEY1 expression has been demonstrated in several tumor types (PMID: 28468863), and HEY1-NCOA2 fusions are recurrent in mesenchymal chondrosarcoma (PMID: 22034177).
Entrez Id 23462
Chromosome 8
Map Location 8q21.13
Canonical Transcript NM_012258


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