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Gene Symbol HEY2
Synonyms bHLHb32 | CHF1 | GRIDLOCK | GRL | HERP1 | HESR2 | HRT2
Gene Description HEY2, hes related family bHLH transcription factor with YRPW motif 2, is a downstream effector of Notch signaling (PMID: 22806875; PMID: 24403239). Overexpression of Hey2 has been observed in several solid tumors, including osteosarcoma, prostate cancer, hepatocellular carcinoma, pancreatic ductal adenocarcinoma, and hemangioma (PMID: 31396342).
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