Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Gene Description||MKRN1, E3 ubiquitin-protein ligase makorin-1, is a zinc-finger protein (PMID: 23104211) and transcriptional coregulator which, inhibits cell death by negative regulation of Tp53 (PMID: 26817873). MKRN1 fusions with BRAF have been observed in pediatric gliomas (PMID: 23817572) and anaplastic thyroid carcinomas (PMID: 26680454) and overexpression of Mkrn1 has been observed in cervical cancer (PMID: 26183061).|