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|Synonyms||12R-LOX | ARCI2|
|Gene Description||ALOX12B, arachidonate 12-lipoxygenase, 12R type, encodes the 12R-LOX enzyme, which oxygenates arachidonic acid and is required for epidermal barrier function (PMID: 23954555, PMID: 24021977). ALOX12B mutations have been observed in large-scale sequencing studies (PMID: 22810696, PMID: 22842228).|