Gene Detail

Gene Symbol FRK
Synonyms GTK | PTK5 | RAK
Gene Description FRK, tyrosine-protein kinase FRK, is a SRC family member that functions in regulation of cell proliferation, differentiation, signaling (PMID: 23318459, PMID: 19652529), and plays a role in genomic stability through BRCA1 (PMID: 29156836). Mutations in FRK are associated with hepatocellular adenomas and lung cancer (PMID: 24735922, PMID: 21074287) and decreased FRK expression has been observed in breast cancer (PMID: 29348886, PMID: 29156836).
Entrez Id 2444
Chromosome 6
Map Location 6q22.1
Canonical Transcript NM_002031

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