Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol GATA3
Synonyms HDR | HDRS
Gene Description GATA3, GATA binding protein 3, is a trans-acting T-cell-specific and zinc-finger transcription factor that regulates development and differentiation (PMID: 7550312) and plays a vital role in immune function (PMID: 21924928). GATA3 regulates tumor differentiation in breast cancer (PMID: 20189993, PMID: 28703335), suppresses neoplastic transformation of urothelial cells (PMID: 25232488), and is frequently mutated in breast cancer (PMID: 32232341).
Additional content available in CKB BOOST