Gene Detail

Gene Symbol LATS2
Synonyms KPM
Gene Description LATS2, serine/threonine-protein kinase LATS2, is a negative regulator of YAP1 in the Hippo signaling pathway, which plays a role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. LATS2 plays a role as a tumor suppressor in human cancer (PMID: 24026096).
Entrez Id 26524
Chromosome 13
Map Location 13q12.11
Canonical Transcript NM_014572

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