Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||DEE17 | EIEE17 | G-ALPHA-o | GNAO | HG1G | HLA-DQB1 | NEDIM|
|Gene Description||GNAO1, G protein subunit alpha o1, is a subunit of the heterotrimeric G protein, which plays a role in transducing cellular signals (PMID: 24366063). Hypermethylation of GNAO1 and subsequent down regulation of expression may play a role in promoting tumorigenesis in hepatocellular carcinoma (PMID: 29709639, PMID: 23984917), however in gastric cancer, overexpression of Gnao1 may correlate with poor prognosis (PMID: 24366063).|