Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol ANGPT1
Synonyms AGP1 | AGPT | ANG1
Gene Description ANGPT1, angiopoietin 1, promotes angiogenesis through the Tie2 receptor, leading to cell proliferation, migration, and cell invasion (PMID: 20651738, PMID: 27703260). Increased expression of Angpt1 has been observed in a variety of cancers, including ovarian and prostate (PMID: 27703260), while decreased expression has been observed in lung squamous cell carcinoma and lung adenocarcinoma (PMID: 31385379).


Additional content available in CKB BOOST