Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||JCK | NEK12A | NPHP9 | RHPD2|
|Gene Description||NEK8, NIMA related kinase 8, is a serine/threonine kinase of the never-in-mitosis A (NIMA) family which regulates mitotic entry (PMID: 23132929), cilia disassembly, and activation of the DNA damage response (PMID: 30333866, PMID: 27892797). NEK8 mutations have been identified in renal and breast cancer (PMID: 25451921, PMID: 15019993), and overexpression has been associated with decreased survival in gastric cancer (PMID: 30333866).|