Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||CRISTIN3 | RSPO|
|Gene Description||RSPO1, R-spondin 1, encodes for one of the secreted proteins in the TSR1-containing protein family, which plays a role in canonical Wnt signaling and ovarian development (PMID: 27270435). RSPO1 amplification has been identified in ovarian cancer and loss of function mutations in squamous cell carcinoma (PMID: 27270435).|