Gene Detail

Gene Symbol RSPO1
Synonyms CRISTIN3 | RSPO
Gene Description RSPO1, R-spondin 1, encodes for one of the secreted proteins in the TSR1-containing protein family, which plays a role in canonical Wnt signaling and ovarian development (PMID: 27270435). RSPO1 amplification has been identified in ovarian cancer and loss of function mutations in squamous cell carcinoma (PMID: 27270435).
Entrez Id 284654
Chromosome 1
Map Location 1p34.3
Canonical Transcript NM_001242908

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