Gene Detail
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| Gene Symbol | GRN | ||||||||||
| Synonyms | CLN11 | GEP | GP88 | PCDGF | PEPI | PGRN | ||||||||||
| Gene Description | GRN, granulin precursor, encodes a growth factor that plays a role in cell growth and survival (PMID: 10858277, PMID: 29263224), including neurite outgrowth and neuronal survival (PMID: 18378771, PMID: 19860916), and the regulation of inflammatory responses (PMID: 27527809). Overexpression of GRN has been identified in several tumor types (PMID: 29116422, PMID: 35116716), including cholangiocarcinoma (PMID: 22068162, PMID: 29403285), prostate cancer (PMID: 14977833), and breast cancer (PMID: 21792312, PMID: 22088468). | ||||||||||
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