Gene Detail


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Gene Symbol TBK1
Synonyms FTDALS4 | IIAE8 | NAK | T2K
Gene Description TBK1, TANK binding kinase 1, is involved in innate immune response and autophagy (PMID: 33454423, PMID: 30223576), and plays a role in regulation of NF-kappaB (PMID: 10581243) and AKT (PMID: 21464307). TBK1 overexpression has been demonstrated in breast (PMID: 24449872) and colon cancer (PMID: 16537575), and in hepatocellular carcinoma (PMID: 33679751).
Additional content available in CKB BOOST