Gene Detail


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Gene Symbol GUCY2C
Synonyms DIAR6 | GC-C | GUC2C | MECIL | MUCIL | STAR
Gene Description GUCY2C, guanylate cyclase 2C, is a heat-stable enterotoxin receptor that binds guanylin and uroguanylin and is expressed in the intestinal epithelium (PMID: 28162021, PMID: 29210639). Aberrant expression of Gucy2c has been observed in colorectal cancer (PMID: 28162021), where it may function as an intestinal tumor suppressor (PMID: 29210639).
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