Gene Detail

Gene Symbol A1CF
Synonyms ACF | ACF64 | ACF65 | APOBEC1CF | ASP
Gene Description A1CF, APOBEC1 complementation factor, is an RNA binding protein and part of a complex which edits the mRNA of apolipoprotein B (PMID: 11871661). Deletion of an eight amino acid motif in the nuclear localization domain of A1cf has been demonstrated to promote breast cancer proliferation in culture (PMID: 27231908) and decreased expression increased apoptosis of breast cancer cells in culture (PMID: 28639893).
Entrez Id 29974
Chromosome 10
Map Location 10q11.23
Canonical Transcript NM_138932

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