Gene Detail

Gene Symbol H2AFX
Synonyms H2A.X | H2A/X | H2AX
Gene Description H2AFX, histone H2AX, encodes a member of the histone H2A family and plays a role in transcription regulation, DNA repair, DNA replication, and chromosomal stability (PMID: 27813335). H2AFX phosphorylation is a biomarker for DNA double-strand break in human cancer progression (PMID: 24206133; PMID: 24164298, PMID: 27813335).
Entrez Id 3014
Chromosome 11
Map Location 11q23.3
Canonical Transcript NM_002105


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